Thursday, 3 January 2013
2.10 understand how the functioning of enzymes can be affected by changes in active site caused by changes in pH
Change in PH can denature enzymes by breaking the bonds that hold the structure in place. So the active site no longer fits with the the substrate it is meant to be breaking down. The PH at which this happens is different for different enzymes, but generally an extreme PH will denature any enzyme.